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Modern Health Pharmacy LDN Program

Low Dose Naltrexone (LDN)

What is LDN?
Low Dose Naltrexone (LDN) is a safe, well-tolerated, and non-toxic therapy that works by gently modulating the immune system. Unlike standard high-dose naltrexone (typically used for opioid addiction), LDN is prescribed at doses typically ranging from 0.5mg to 4.5mg—about one-tenth or less of the standard dosage. This unique approach allows it to regulate a variety of bodily systems without narcotic effects.

How It Works
LDN temporarily blocks opioid receptors, prompting the body to increase the production of endorphins (your natural feel-good hormones). This “rebound” effect can restore balance to the immune system and reduce chronic inflammation. LDN also interacts with Opioid Growth Factor (OGF) receptors, which are found throughout the body and play a key role in immune function and cell regulation.

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Conditions LDN May Help With

LDN is being explored—and in many cases successfully used—for a wide range of chronic and complex conditions. Some of the most common include:

Autoimmune Disorders

LDN helps calm an overactive immune response, offering relief in:

  • Hashimoto's Thyroiditis

  • Multiple Sclerosis (MS)

  • Rheumatoid Arthritis

  • Lupus

  • Psoriasis and Psoriatic Arthritis

  • Inflammatory Bowel Disease (Crohn's and Ulcerative Colitis)

Chronic Pain Conditions

LDN can reduce central nervous system inflammation and is being used for:

  • Fibromyalgia

  • Complex Regional Pain Syndrome (CRPS)

  • Interstitial Cystitis

  • Migraines and Chronic Headaches

Mental Health & Neurological Disorders

Due to its immune-balancing and neuroprotective effects, LDN shows promise for:

  • Depression

  • Anxiety

  • PTSD

  • Autism Spectrum Disorders

  • Parkinson’s Disease

Cancer Support

While not a standalone cancer treatment, LDN may enhance quality of life and immune function in patients with:

  • Breast Cancer

  • Ovarian Cancer

  • Prostate Cancer

  • Pancreatic and Colorectal Cancers

Thyroid Support

In some patients, LDN has led to improvements in thyroid function, especially in cases of autoimmune thyroiditis when used alongside appropriate thyroid medications.

Long COVID and ME/CFS

Emerging research and anecdotal reports suggest LDN may help manage symptoms like brain fog, fatigue, and body pain associated with:

  • Long COVID

  • Chronic Fatigue Syndrome (ME/CFS)

Women’s Health

LDN is also being investigated for use in:

  • Endometriosis

  • Polycystic Ovary Syndrome (PCOS)

  • Chronic pelvic pain

Why Choose Modern Health Pharmacy for LDN?

At Modern Health Pharmacy, we specialize in compounding personalized LDN therapies to meet individual needs. Whether you're new to LDN or exploring it as part of a broader health strategy, our pharmacists can work closely with your provider to determine the right dosage and formulation (capsules, liquids, creams, etc.).

We stay up-to-date with the latest LDN research and support protocols that align with ongoing clinical findings, ensuring safe and effective outcomes.

References and Further Reading

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Wegovy® and Zepbound® are trade marks of Eli Lilly and Novo Nordisk
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